CD70 and nonpapillary renal cell carcinoma: BMS-936561, also called MDX-1203, is composed of human IgG1 conjugated with a MED-2460 or duocarmycin molecule through a peptide-based linker directed against CD70, and it was evaluated in patients with advanced clear cell RCC (ccRCC) and B lymphocyte-NHL (B-NHL) (NCT00944905) [40].