Post hoc analysis revealed a statistically significant difference in RANK expression between the tumor front (mean rank 2.46) and tumor back (mean rank 1.38) (p = 0.024) in the E group and a statistically significant difference in RANK expression between the tumor front (mean rank 2.50) and tumor back (1.25) (p = 0.016) in the I group. The gene discussed is TNFRSF11A; the disease is neoplasm.