RANKL expression, assessed by Friedman’s test, was significantly different in all patient groups comparing normal mucosa, tumor back, tumor center and tumor front; NI group (χ2(3) = 12.60, p = 0.006), E group (χ2(3) = 17.855, p < 0.001) and I group (χ2(3) = 17.468, p = 0.001). Here, TNFSF11 is linked to neoplasm.