In particular, in the Copenhagen General population study (100,520 subjects with a follow-up of 8.5 years), it emerged that for each 1 g/dL lower albumin level (hypoalbuminemia defined as <3.5 g/dL), the Hazard Ratios (HRs) were 1.17 for ischemic heart disease, 1.25 for myocardial infarction, 1.37 for any stroke, and 1.46 for ischemic stroke [35]. The gene discussed is ALB; the disease is coronary artery disorder.