In addition, the median IL-1β concentration was significantly higher in the group of men with IBD than in the group of women with IBD (3.0 pg/mL vs. 2.8 pg/mL, p = 0.0422) and in the group of patients with a positive family history (3.1 pg/mL vs. 2.9 pg/mL, p = 0.0437). The gene discussed is IL1B; the disease is inflammatory bowel disease.