FLT1 and preeclampsia: Various studies have demonstrated that an angiogenic imbalance in preeclampsia, reflected by excessive placental secretion of the circulating anti-angiogenic molecule, soluble fms-like tyrosine kinase-1 (sFlt-1) and decreased angiogenic placental growth factor (PlGF) levels in the maternal circulation, is present in preeclampsia [23,24].