In our previous article on patients with CKD in whom FGF23 increased steadily as in the KTx patients, the landscape was completely reversed with a significant decrease in CV-protective n-3 from CKD 3 to 4 and a significant increase in pro-inflammatory n-6 from CKD 3 to 5 and from CKD 4 to 5. Here, FGF23 is linked to chronic kidney disease.