The following predictors and risk factors were examined for their influence on HHS ≤ 3 months postoperatively: patient age, BMI, preoperative HHS, sex, osteoarthritis, femoral neck fracture, dysplasia, ANFH, surgical approach, operation time, incision length, intraoperative blood loss, acetabular cup inclination, CRP 1–3 days postoperatively, CK 1–3 days postoperatively, and use of bone cement. This evidence concerns the gene CRP and familial avascular necrosis of femoral head.