This study investigated specific markers related to vitiligo pathogenesis as redox status (TAS, SOD, GPx, CAT, MDA, and AOPP), inflammatory profile (CRP), innate immunity (IL-15), and adaptive immunity (CXCL9 and CXCL10) markers in patients with non-segmental vitiligo, which is the most prevalent type of vitiligo in comparison to healthy controls. This evidence concerns the gene SOD1 and vitiligo.