Regarding Loxl3, the conditional L3-KO model generated in the context of mouse melanoma (Table 3) has been instrumental in supporting a key action of Loxl3 in melanomagenesis and lymphatic dissemination of cutaneous melanoma [143], which agrees with the high expression levels of LOXL3 found in association with SNAI1 and other EMT factors in human melanoma samples and cell lines [143,146]. This evidence concerns the gene LOXL3 and cutaneous melanoma.