Notably, ADH4, a unique protein of Group G involved in the catabolism of a variety of substrates such as ethanol, retinol, steroids, and lipids [32,33], has been demonstrated to be a key gene for energy metabolism in cancer cells [34] and can be critical in energy metabolism in the liver and ovary in Group G. Among the DEPs identified in the liver of Group H, only one DEP was enriched in a unique pathway related to carbohydrate metabolism. This evidence concerns the gene ADH4 and cancer.