In the study by Kuboyama et al. [149], the therapeutic effects of 570 nm LED light and 940 nm light on arthritis in mice were compared, and the results showed that 940 nm light had a better swelling reduction effect and was also more effective in inhibiting proinflammatory factors such as IL-1β, IL-6, and MMP-3. This evidence concerns the gene IL1B and arthritic joint disease.