PSEN1 and early-onset autosomal dominant Alzheimer disease: In addition, the findings indicated that the beneficial effects of ginsenoside F1 extended to an improvement in the amyloid precursor protein/presenilin 1 (APP/PS1) transgenic mouse model of Alzheimer’s disease [19,20,21,22], In this study, our objective was to evaluate the potential impact of F1 on telomeres, as well as investigate the subsequent effects on mitochondrial function and alterations in the profile of cellular senescence.