Notably, JARID2 exhibited the highest overlap with CHARGE (~7%, CHD7), BAFopathy (~4%, including ARID1A, ARID1B, SMARCB1, SMARCA2, SMARCA4), and the PCR2 complex, which houses Cohen–Gibson syndrome (COGIS) and Weaver syndrome (WVS) (~4%, EED, EZH2) (Figure 4). Here, JARID2 is linked to Cohen-Gibson syndrome.