A further RCT [39] in a selected high-risk population of 80 PCOS patients who received r-FSH for ovarian stimulation in GnRH-ant IVF cycles compared the administration of different hCG doses for triggering, i.e., 10,000 IU vs. 5000 IU vs. 2500 IU. This evidence concerns the gene BRD2 and polycystic ovary syndrome.