MBNL1 and myotonic dystrophy type 2: The important role of MBNL1 in both DM1 and DM2 pathogenesis is also supported by the evidence that cardiac overexpression of Mbnl, the Drosophila MBNL1 ortholog, is sufficient to rescue the heart dysfunctions and the reduced survival observed in the DM1 and DM2 fly models [37].