PLAT and myocardial infarction: Though thrombolysis has been widely replaced by primary percutaneous coronary stenting (PCI) in the setting of myocardial infarction, thrombolysis with recombinant tPA is still used for the treatment of pulmonary embolus [15] and, most notably, in the treatment of ischaemic stroke where the beneficial effect on mortality and functional outcome after stroke has been firmly established [16].