An in vitro study with the human neuroblastoma SH-SY5Y cell line observed that TUDCA prevented oxidative stress through the highest expression of NRF2, DJ-1, and antioxidant enzymes heme oxygenase-1 (HO-1) and glutathione peroxidase (GPx) [42], corroborating with our results. Here, NFE2L2 is linked to neuroblastoma.