Among inflammatory markers, CXCL12, CCL17, and IL6 are prevalently expressed in the skin surrounding BCC suggesting a role in Treg attraction and immune suppression, although CCL22 and CCL18 are present in both tumoral and peritumoral skin and CCL25 is specifically upmodulated in the BCC lesion [307]. This evidence concerns the gene CXCL12 and skin basal cell carcinoma.