CDKN2B-AS1 and diabetic retinopathy: ANRIL knockdown and HRECs following ANRIL siRNA transfection showed a reduction in p300 mRNA expression, and it had been previously revealed that there was increased production of p300 in diabetic retinopathy mediated by miR200b and that glucose-induced upregulation of VEGF was prevented by a miR200b blocker.