Regarding POLD4 expression and mRNAsi score, a majority of cancer types exhibited a negative association, including GBM, TGCT, LAML, LGG, UCS, BRCA, BLCA, DLBC, READ, HNSC, LUSC, CESC, SKCM, THCA, COAD, LIHC, LUAD, and OV (Figure S12B). Here, POLD4 is linked to cancer.