Based on available literature data, interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), and neuronal injury markers like S100 calcium-binding protein B (S100B) could potentially play a role in OSA management [12,13,14,15,16]. This evidence concerns the gene CRP and obstructive sleep apnea syndrome.