CD8A and Myelodysplasia: The normal ratio of CD4/CD8 is ≥1.8 [25], and an inverted ratio (i.e., <1) has traditionally been associated with immune senescence, myelodysplasia, and persistent viral infections such as HIV (Human immunodeficiency virus), HCMV (Human cytomegalovirus), and EBV (Epstein–Barr virus) [25,26,27].