In addition to wt_p53 loss of functions, mutant p53 (mut_p53) enhances oncogenic features of cancer cells (gain-of-function activities) [8,9,10]: for instance, mut_p53 promotes the invasiveness of cancer cells by epithelial-mesenchymal transition (EMT) through the regulation of Zeb1 and Twist1 transcription factors [2,6,11,12]. The gene discussed is TP53; the disease is cancer.