Human LSM4 was indicated among the Differentially Expressed Autophagy-Related Genes (DE-ARGs) in a study that aimed to find interactions between autophagy and hepatocellular carcinoma (HCC) pathogenesis [47], but, up to now, there has been no evidence of the direct involvement of LSM4 in autophagy [47]. This evidence concerns the gene LSM4 and hepatocellular carcinoma.