Canonical pathway analysis showed enrichment (−log (B-H p-value) > 1.3) of the following pathways: RhoA signaling and regulation of actin-based motility by Rho, caveolar-mediated endocytosis signaling, cross talk between dendritic cells and natural killer cells, integrin signaling, Huntington’s disease signaling, clathrin-mediated endocytosis signaling, and RhoA signaling and phagosome maturation (Figure 3a, Table S2). This evidence concerns the gene RHO and juvenile Huntington disease.