CD4 and ovarian carcinoma: CD4+ and CD8+ tumor-infiltrating lymphocytes (TILs) have been associated with improved OS and progression-free survival (PFS) in all epithelial ovarian cancers [11,22,23,24,25,26,27], including the high-grade serous [28,29], mucinous [25], clear cell [30], and endometrioid [31] types.