Additionally, vascular endothelial growth factor D, lactosylceramide 4-alpha-galactosyltransferase, ARL14 effector protein, ER membrane protein complex subunit, CD40 ligand, Ras-like protein family member 11A, protein YIPF4, tetraspanin-3, uncharacterized protein C22orf46, proteasome subunit alpha type-6, and mannose-P-dolichol utilization defect 1 protein were not found in any of the patients with lymph node metastases, but these proteins were detected in 40% of non-metastatic patients. This evidence concerns the gene PROS1 and metastatic malignant neoplasm in the lymph nodes.