However, since the production of Th2-related cytokines such as interleukins 4, 5, and 13 (IL-4, IL-5, and IL-13) has been confirmed in further cell populations as type 2 innate lymphoid cells (ILC-2s), mast cells, basophils, and/or eosinophils, the term Th2 has been currently updated to the T2 immune phenotype in asthma [14]. This evidence concerns the gene IL4 and asthma.