The only GWAS of T2-low adult asthma (n = 1350) revealed a genome-wide significant association (rs117639512, OR for A allele = 0.33, p-value = 2.75 × 10−8) in the intergenic region between kallikrein-related peptidase 4 (KLK4) and kallikrein-related peptidase 5 (KLK5) genes [101]. Here, KLK5 is linked to asthma.