LDHA and breast neoplasm: Nevertheless, it appears that ALDH1A1 is an important target of disulfiram, as the latter could inhibit breast tumor growth and tumorigenesis by purging ALDH+ cancer stem cells and activating T-cell immunity in xenografted mice, where it was shown that breast cancer cells expressing ALDH1A1 remodel myeloid-derived suppressor cells to enable cancer progression [69].