We recently reviewed 42 SNPs within ACE2 (12), TMPRSS2 (10), NRP1 (15) and CD147 (5) and found that rs2285666 (ACE2), rs12329769 (TMPRSS2), rs10080 (NRP1) and rs8259 (CD147) are significantly associated with COVID-19 co-morbidities within European and South Asian settings [9]. The gene discussed is ACE2; the disease is COVID-19.