A comparison between 532 non-obese French young adults and 505 obese French children showed an association between PCSK1 rs6232 (OR: 1.57, p: 0.009) and rs6235 (OR: 1.50 (1.23, p: 0.00003) and obesity, results consistent with this study [33]. Here, PCSK1 is linked to obesity due to melanocortin 4 receptor deficiency.