AMBL was found to express ABCG2 [13], ALDH1 [34], BMI1 [13,40], CD133 [13], CD166 [41], CD44 [12,31,44], and c-Myc [45] in peripheral and/or central cells of the parenchyma at variable extent and intensity levels, as well as CD34 in spindle-shaped stomal cells [10] and LGR5 [39] and NANOG [10,14] in both epithelial and stromal tumor components. The gene discussed is LGR5; the disease is neoplasm.