Additionally, our CompG models showed that 25 SNP pairs mapped to the CLU locus (β coefficients ranged from −0.288 to 0.386) and 24 SNP pairs mapped to the ABCA7 locus (β coefficients ranged from −0.282 to 0.186) were associated with AD, while their comprising SNPs were not associated with AD in the single SNP models (Table 3, Table 4, Tables S3 and S5). This evidence concerns the gene ABCA7 and Alzheimer disease.