PGF and fetal growth restriction: Moreover, among patients already diagnosed with early fetal growth restriction (<32 weeks), Palma Dos Reis [49] demonstrated that sFlt-1/PLGF values > 85 measured when the diagnosis was established were associated with a shorter time until delivery (1.9 ± 1.52 weeks vs. 5.7 ± 3.2 weeks for sFlt-1/PlGF ≤ 85), as well as higher prevalence of fetal demise, albeit independently of pre-eclampsia.