DAPK1 and nasopharyngeal carcinoma: The methylation of the DAPK gene was associated with an increased NPC risk with pooled OR of 13.13, based on the random-effect model (Q = 64.74, p < 0.0001, I2 = 81.47%, 95%CI for I2 = 69.39–88.78) (Figure 3).