The human normal colon epithelial cells, CCD 841 CoTr, human colon adenocarcinoma cells (LoVo), human colon adenocarcinoma cells resistant to Doxorubicin (LoVo/Dx), human Caucasian lung carcinoma (A549), human breast cancer cell line with estrogen, progesterone and glucocorticoid receptors (MCF7), and Caucasian acute lymphoblastic leukemia A T lymphoblastoid line (CCRF/CEM) were used in the research. The gene discussed is NR3C1; the disease is colon adenocarcinoma.