Among 189 adult subjects (91 males (M) and 98 females (F)) with diabetes and GAD-positive autoantibodies included in the study, ZnT8 autoantibodies were detected in 81 subjects (M/F = 38/53) and IA-2 autoantibodies in 67 subjects (M/F = 27/40) while 91 subjects (M/F = 53/38) had only GADA positivity. This evidence concerns the gene PTPRN and diabetes mellitus.