Recently, Huh et al. tried to uncover novel diagnostic biomarkers for HG serous ovarian cancer via data-independent acquisition mass spectrometry, and succeeded in identifying a total of four potential biomarkers (fibrinogen-A, von-Willebrand factor, rho GDP dissociation inhibitor beta, and serpin family F member) that might play a significant role in HG serous ovarian cancer cell proliferation and migration [28]. This evidence concerns the gene ARHGDIB and ovarian serous adenocarcinoma.