Recently, it has also been shown that these three TGF-β isoforms are all detected within aqueous humor (AH) [27], suggesting their contribution to the pathogenesis of glaucoma [28,29,30], and among these, AH levels of TGF-β2 were most abundant in patients with glaucoma as well as healthy subjects [28]. The gene discussed is TGFB1; the disease is glaucoma.