TNNI3 and hydrops fetalis: These cardiac biomarkers were also significantly restored in group pretreatment with 7-HF (25 mg/kg) + ISO, cTnI (0.611 ± 0.01), CK-MB (134.53 ± 6.73), LDH (342.73 ± 9.15), ALT (39.75 ± 1.60) and AST (54.45 ± 4.01), compared to ISO-alone treated group (Figure 4A–E).