ALDH1A1 and Hypertension: Another gene that seems to be related to both liver physiology and hypertension-NAFLD interaction is the aldehyde dehydrogenase (ALDH1A1, alternatively known as retinaldehyde dehydrogenase 1 or RALDH1) gene, encoding the enzyme which catalyzes the second and irreversible step of retinaldehyde oxidation to vitamin A (retinoic acid) [141].