PNPLA3 and metabolic dysfunction-associated steatotic liver disease: Genome-wide association studies (GWASs) have identified dozens of genetic variants related to NAFLD over the last decade, such as patatin-like phospholipase domain-containing protein 3 (PNPLA3), Glucokinase regulatory protein (GCKR) and Membrane Bound O-Acyltransferase Domain Containing 7 (MBOAT7) [5,6,7].