EDN1 and coronary artery disorder: Three risk SNPs associated with CAD severity in the log-additive inheritance model were discovered: two variants in the maintenance of endothelial homeostasis genes—EDN1 rs5370, OR = 2.18, 95% CI = 1.23–3.88, p = 0.008 and EDN1 rs3087459, OR = 1.89, 95% CI = 1.04–3.44, p = 0.04; and one variant in the vitamin D metabolism genes—GC rs2298849 (OR = 2.26, 95% CI = 1.28–3.99, p = 0.006) (Table 3).