AKT1 and head and neck squamous cell carcinoma: Various natural products, namely actein, salicylate, tanshinone IIA, xanthohumol, fucoidan, honokiol, ilimaquinone, nimbolide, and cinnamaldehyde, have led to the downregulation of Akt expression and phosphorylation of Akt (p-Akt) using HNSCC preclinical models [41,42,43,44,45,46,47,48,49].