EGFR and head and neck squamous cell carcinoma: For example, psorachromene, a flavonoid found in Psoralea corylifolia, which has been used in traditional Chinese medicine (TCM) and Ayurveda, had shown therapeutic effects against HNSCC via regulation of the EGFR signaling pathways and other carcinogenesis-related signaling pathway, making it a strong candidate to act as a chemotherapeutic agent [24].