Our study showed that membrane transport (ribose transport system), transcription (AraC family transcription regulator), and metabolism (cysteine-S-conjugate beta-lyase) are enriched in stroke patients while amino acid metabolism (glutamate synthase), replication and repair (ATP-dependent DNA helicase RecG), and metabolism of cofactors and vitamins (thiamine-phosphate pyrophosphorylase) are depleted in stroke patients. The gene discussed is KYAT1; the disease is Stroke.