The antiproliferative activity of atorvastatin was connected with the induction of apoptosis, autophagy, cellular stress, and cell cycle G1 arrest through the inhibition of AKT/mTOR and the activation of the MAPK pathways. In addition, atorvastatin inhibited cell adhesion, invasion, and decreased the expression of VEGF and MMP 9. c-Myc was downregulated in ovarian cancer,. The gene discussed is AKT1; the disease is ovarian carcinoma.