Interestingly, myofibroblast-like and other CAF sub-populations expressing EphA3 are known to have immune-suppressive activity in tumours [53,54], and we observed increased cytotoxic T cell infiltration into tumours in mice with EphA3 knockdown, suggesting possible implications for enhanced anti-tumour immune response as a subject for future investigation. The gene discussed is EPHA3; the disease is neoplasm.