The ACHE gene was shown to be downregulated, upregulated, and unchanged in solid tumors (Figure 5); therefore, using UALCAM [79,80] and KMplot [81] web tools, we analyzed the expression profile of the ACHE gene at the mRNA level in the five common causes of cancer death worldwide reported by the International Agency for Research on Cancer in 2020 (lung, colorectum, liver, stomach, and breast cancer) [82,83]. This evidence concerns the gene ACHE and cancer.