Positron emission tomography (PET) has gained particular attention for the restaging of PCa due to the introduction of new radiotracers, such as [68Ga]Ga-PSMA-11, that have better sensitivity and specificity for the detection of metastatic disease, compared to conventional imaging, also at low PSA levels [12,13,14]. Here, FOLH1 is linked to posterior cortical atrophy.