IL6 and head and neck squamous cell carcinoma: This contrasts with studies on HNSCC cell lines, which found that irradiation (2, 5 and 10 Gy) stimulated the release of IL6 within 24 h post-irradiation from fibroblasts, which will be present in the tumour biopsy samples, as well as reducing the survival of HNSCC cells [62].