IL6 and neoplasm: You et al. [13] identified Insulin-like Growth Factor 1 Receptor (IGF1R), Laminin Subunit Gamma 2 (LAMC2), Integrin Subunit Beta 1 (ITGB1) and Interleukin-6 (IL6) as “key” molecules associated with poor survival in HNSCC patients receiving radiotherapy, and Kim et al. [14] found that specific radio resistance signatures could predict outcome following radiation in HPV negative HNSCC, but that tumour subtype needed to be taken into consideration.